Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM053007-06
Application #
6383626
Study Section
Cell Development and Function Integrated Review Group (CDF)
Program Officer
Rhoades, Marcus M
Project Start
1995-08-01
Project End
2005-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
6
Fiscal Year
2001
Total Cost
$222,198
Indirect Cost
Name
Brandeis University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Metkar, Mihir; Ozadam, Hakan; Lajoie, Bryan R et al. (2018) Higher-Order Organization Principles of Pre-translational mRNPs. Mol Cell 72:715-726.e3
Braun, Joerg E; Friedman, Larry J; Gelles, Jeff et al. (2018) Synergistic assembly of human pre-spliceosomes across introns and exons. Elife 7:
Chen, Weijun; Moore, Jill; Ozadam, Hakan et al. (2018) Transcriptome-wide Interrogation of the Functional Intronome by Spliceosome Profiling. Cell 173:1031-1044.e13
Cenik, Can; Chua, Hon Nian; Singh, Guramrit et al. (2017) A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and N1-methyladenosine modification. RNA 23:270-283
Serebrov, Victor; Moore, Melissa J (2016) Single Molecule Approaches in RNA-Protein Interactions. Adv Exp Med Biol 907:89-106
Hoskins, Aaron A; Rodgers, Margaret L; Friedman, Larry J et al. (2016) Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. Elife 5:
Singh, Guramrit; Pratt, Gabriel; Yeo, Gene W et al. (2015) The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annu Rev Biochem 84:325-54
Salomon, William E; Jolly, Samson M; Moore, Melissa J et al. (2015) Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides. Cell 162:84-95
Chen, Weijun; Moore, Melissa J (2014) The spliceosome: disorder and dynamics defined. Curr Opin Struct Biol 24:141-9
Chen, Weijun; Shulha, Hennady P; Ashar-Patel, Ami et al. (2014) Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes. RNA 20:308-20

Showing the most recent 10 out of 35 publications