Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054065-01
Application #
2193461
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Michigan State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Proshlyakov, Denis A; McCracken, John; Hausinger, Robert P (2017) Spectroscopic analyses of 2-oxoglutarate-dependent oxygenases: TauD as a case study. J Biol Inorg Chem 22:367-379
Cappillino, Patrick J; Miecznikowski, John R; Tyler, Laurie A et al. (2012) Studies of iron(II) and iron(III) complexes with fac-N2O, cis-N2O2 and N2O3 donor ligands: models for the 2-His 1-carboxylate motif of non-heme iron monooxygenases. Dalton Trans 41:5662-77
Sharpe, Martyn A; Krzyaniak, Matthew D; Xu, Shujuan et al. (2009) EPR evidence of cyanide binding to the Mn(Mg) center of cytochrome c oxidase: support for Cu(A)-Mg involvement in proton pumping. Biochemistry 48:328-35
Mills, Denise A; Xu, Shujuan; Geren, Lois et al. (2008) Proton-dependent electron transfer from CuA to heme a and altered EPR spectra in mutants close to heme a of cytochrome oxidase. Biochemistry 47:11499-509
McCracken, John; Vassiliev, Ilya R; Yang, En-Che et al. (2007) ESEEM studies of peptide nitrogen hyperfine coupling in tyrosyl radicals and model peptides. J Phys Chem B 111:6586-92
Velayutham, Murugesan; Muthukumaran, Rajendra B; Sostaric, Joe Z et al. (2007) Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention. Free Radic Biol Med 43:1076-85
Muthukumaran, Rajendra Bose; Grzyska, Piotr K; Hausinger, Robert P et al. (2007) Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy. Biochemistry 46:5951-9
Schmidt, Bryan; Hillier, Warwick; McCracken, John et al. (2004) The use of stable isotopes and spectroscopy to investigate the energy transducing function of cytochrome c oxidase. Biochim Biophys Acta 1655:248-55
Henshaw, Timothy F; Feig, Michael; Hausinger, Robert P (2004) Aberrant activity of the DNA repair enzyme AlkB. J Inorg Biochem 98:856-61
Ryle, Matthew J; Liu, Aimin; Muthukumaran, Rajendra Bose et al. (2003) O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase. Biochemistry 42:1854-62

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