Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054709-01
Application #
2194046
Study Section
Special Emphasis Panel (ZRG2-ALY (01))
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Pathology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Sandoval, Raudel; Pilkinton, Mark; Colamonici, Oscar R (2009) Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex. Exp Cell Res 315:2914-20
Pilkinton, Mark; Sandoval, Raudel; Barrett, Kelly et al. (2007) Mip/LIN-9 can inhibit cell proliferation independent of the pocket proteins. Blood Cells Mol Dis 39:272-7
Pilkinton, Mark; Sandoval, Raudel; Song, Julie et al. (2007) Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1. J Biol Chem 282:168-75
Pilkinton, M; Sandoval, R; Colamonici, O R (2007) Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex. Oncogene 26:7535-43
Sandoval, Raudel; Xue, Jiaping; Tian, Xinyong et al. (2006) A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes. Exp Cell Res 312:2465-75
Datta, Abhishek; Nag, Alo; Pan, Wei et al. (2004) Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc. J Biol Chem 279:36698-707
Sandoval, Raudel; Xue, Jiaping; Pilkinton, Mark et al. (2004) Different requirements for the cytostatic and apoptotic effects of type I interferons. Induction of apoptosis requires ARF but not p53 in osteosarcoma cell lines. J Biol Chem 279:32275-80
Usacheva, Anna; Tian, Xinyong; Sandoval, Raudel et al. (2003) The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex. J Immunol 171:2989-94
Usacheva, Anna; Sandoval, Raudel; Domanski, Paul et al. (2002) Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation. J Biol Chem 277:48220-6
Prejean, C; Sarma, T; Kurnasov, O et al. (2001) Phosphatidylinositol 3-kinase confers resistance to encephalomyocarditis and herpes simplex virus-induced cell death through the activation of distinct downstream effectors. J Immunol 167:4553-9

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