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Dou, Zhixun; Pan, Ji-An; Dbouk, Hashem A et al. (2013) Class IA PI3K p110? subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Mol Cell 50:29-42
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Salamon, Rachel Schnur; Backer, Jonathan M (2013) Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases. Bioessays 35:602-11
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Dbouk, Hashem A; Khalil, Bassem D; Wu, Haiyan et al. (2013) Characterization of a tumor-associated activating mutation of the p110* PI 3-kinase. PLoS One 8:e63833
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Dbouk, Hashem A; Backer, Jonathan M (2013) Novel approaches to inhibitor design for the p110? phosphoinositide 3-kinase. Trends Pharmacol Sci 34:149-53
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Vadas, Oscar; Dbouk, Hashem A; Shymanets, Aliaksei et al. (2013) Molecular determinants of PI3K?-mediated activation downstream of G-protein-coupled receptors (GPCRs). Proc Natl Acad Sci U S A 110:18862-7
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Dbouk, Hashem A; Vadas, Oscar; Shymanets, Aliaksei et al. (2012) G protein-coupled receptor-mediated activation of p110? by G?? is required for cellular transformation and invasiveness. Sci Signal 5:ra89
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Smirnova, T; Zhou, Z N; Flinn, R J et al. (2012) Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis. Oncogene 31:706-15
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Yoon, Mee-Sup; Du, Guangwei; Backer, Jonathan M et al. (2011) Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway. J Cell Biol 195:435-47
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Ciraolo, Elisa; Morello, Fulvio; Hobbs, Robin M et al. (2010) Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility. Mol Biol Cell 21:704-11
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Dbouk, Hashem A; Backer, Jonathan M (2010) A beta version of life: p110? takes center stage. Oncotarget 1:729-33
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Showing the most recent 10 out of 21 publications
