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Sontag, Emily Mitchell; Samant, Rahul S; Frydman, Judith (2017) Mechanisms and Functions of Spatial Protein Quality Control. Annu Rev Biochem 86:97-122
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Hanebuth, Marie A; Kityk, Roman; Fries, Sandra J et al. (2016) Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction. Nat Commun 7:13695
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Chartron, Justin W; Hunt, Katherine C L; Frydman, Judith (2016) Cotranslational signal-independent SRP preloading during membrane targeting. Nature 536:224-8
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Shen, Koning; Calamini, Barbara; Fauerbach, Jonathan A et al. (2016) Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract. Elife 5:
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Pechmann, Sebastian; Chartron, Justin W; Frydman, Judith (2014) Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo. Nat Struct Mol Biol 21:1100-5
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Pechmann, Sebastian; Frydman, Judith (2014) Interplay between chaperones and protein disorder promotes the evolution of protein networks. PLoS Comput Biol 10:e1003674
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Sontag, Emily Mitchell; Vonk, Willianne I M; Frydman, Judith (2014) Sorting out the trash: the spatial nature of eukaryotic protein quality control. Curr Opin Cell Biol 26:139-146
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Duttler, Stefanie; Pechmann, Sebastian; Frydman, Judith (2013) Principles of cotranslational ubiquitination and quality control at the ribosome. Mol Cell 50:379-93
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Geller, Ron; Andino, Raul; Frydman, Judith (2013) Hsp90 inhibitors exhibit resistance-free antiviral activity against respiratory syncytial virus. PLoS One 8:e56762
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Willmund, Felix; del Alamo, Marta; Pechmann, Sebastian et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152:196-209
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Showing the most recent 10 out of 37 publications
