Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM056615-07A2S1
Application #
6742389
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Wolfe, Paul B
Project Start
1997-08-01
Project End
2006-12-31
Budget Start
2003-01-01
Budget End
2003-12-31
Support Year
7
Fiscal Year
2003
Total Cost
$9,651
Indirect Cost
Name
Ohio State University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
071650709
City
Columbus
State
OH
Country
United States
Zip Code
43210
Tabah, Azah A; Tardif, Keith; Mansky, Louis M (2014) Anti-HIV-1 activity of Trim 37. J Gen Virol 95:960-7
Dapp, Michael J; Bonnac, Laurent; Patterson, Steven E et al. (2014) Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1. J Virol 88:354-63
Clouser, Christine L; Bonnac, Laurent; Mansky, Louis M et al. (2014) Characterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugs. Antivir Chem Chemother 23:223-30
Holtz, Colleen M; Mansky, Louis M (2013) Variation of HIV-1 mutation spectra among cell types. J Virol 87:5296-9
Dapp, Michael J; Patterson, Steven E; Mansky, Louis M (2013) Back to the future: revisiting HIV-1 lethal mutagenesis. Trends Microbiol 21:56-62
Holtz, Colleen M; Sadler, Holly A; Mansky, Louis M (2013) APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure. Nucleic Acids Res 41:6139-48
Dapp, Michael J; Heineman, Richard H; Mansky, Louis M (2013) Interrelationship between HIV-1 fitness and mutation rate. J Mol Biol 425:41-53
Rawson, Jonathan M; Heineman, Richard H; Beach, Lauren B et al. (2013) 5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors. Bioorg Med Chem 21:7222-8
Greggs 3rd, Willie M; Clouser, Christine L; Patterson, Steven E et al. (2012) Discovery of drugs that possess activity against feline leukemia virus. J Gen Virol 93:900-5
Dapp, Michael J; Holtz, Colleen M; Mansky, Louis M (2012) Concomitant lethal mutagenesis of human immunodeficiency virus type 1. J Mol Biol 419:158-70

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