Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM056779-07
Application #
6690347
Study Section
Special Emphasis Panel (ZRG1-CDF-4 (02))
Program Officer
Shapiro, Bert I
Project Start
1998-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$270,579
Indirect Cost
Name
Carnegie-Mellon University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Song, Lina; Bachert, Collin; Linstedt, Adam D (2016) Activity Detection of GalNAc Transferases by Protein-Based Fluorescence Sensors In Vivo. Methods Mol Biol 1496:123-31
Song, Lina; Bachert, Collin; Schjoldager, Katrine T et al. (2014) Development of isoform-specific sensors of polypeptide GalNAc-transferase activity. J Biol Chem 289:30556-66
Jarvela, Timothy S; Linstedt, Adam D (2014) The application of KillerRed for acute protein inactivation in living cells. Curr Protoc Cytom 69:12.35.1-12.35.10
Tewari, Ritika; Jarvela, Timothy; Linstedt, Adam D (2014) Manganese induces oligomerization to promote down-regulation of the intracellular trafficking receptor used by Shiga toxin. Mol Biol Cell 25:3049-58
Mukhopadhyay, Somshuvra; Linstedt, Adam D (2013) Retrograde trafficking of AB? toxins: mechanisms to therapeutics. J Mol Med (Berl) 91:1131-41
Guo, Yusong; Linstedt, Adam D (2013) Binding of the vesicle docking protein p115 to the GTPase Rab1b regulates membrane recruitment of the COPI vesicle coat. Cell Logist 3:e27687
Mukhopadhyay, Somshuvra; Redler, Brendan; Linstedt, Adam D (2013) Shiga toxin-binding site for host cell receptor GPP130 reveals unexpected divergence in toxin-trafficking mechanisms. Mol Biol Cell 24:2311-8
Bachert, Collin; Linstedt, Adam D (2013) A sensor of protein O-glycosylation based on sequential processing in the Golgi apparatus. Traffic 14:47-56
Grover, Anmol; Schmidt, Brigitte F; Salter, Russell D et al. (2012) Genetically encoded pH sensor for tracking surface proteins through endocytosis. Angew Chem Int Ed Engl 51:4838-42
Jarvela, Timothy; Linstedt, Adam D (2012) Irradiation-induced protein inactivation reveals Golgi enzyme cycling to cell periphery. J Cell Sci 125:973-80

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