Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM058101-06S1
Application #
6838107
Study Section
Medicinal Chemistry Study Section (MCHA)
Program Officer
Schwab, John M
Project Start
1998-09-01
Project End
2007-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
6
Fiscal Year
2004
Total Cost
$68,974
Indirect Cost
Name
University of Pennsylvania
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Stanton, Gretchen R; Kauffman, Meara C; Walsh, Patrick J (2012) Diastereoselective chelation-controlled additions to ?-silyloxy aldehydes. Org Lett 14:3368-71
Hernandez-Toribio, Jorge; Hussain, Mahmud M; Cheng, Kevin et al. (2011) Diastereoselective aziridination of 2-B(pin)-substituted allylic alcohols: an efficient approach to novel organoboron compounds. Org Lett 13:6094-7
Zhang, Jiadi; Stanciu, Corneliu; Wang, Beibei et al. (2011) Palladium-catalyzed allylic substitution with (?6-arene-CH2Z)Cr(CO)(3)-based nucleophiles. J Am Chem Soc 133:20552-60
Hussain, Mahmud M; Hernandez Toribio, Jorge; Carroll, Patrick J et al. (2011) Synthesis of 2-keto-anti-1,3-diols by chemoselective tandem oxidation of 2-B(pin)-substituted allylic alcohols. Angew Chem Int Ed Engl 50:6337-40
Hussain, Nusrah; Hussain, Mahmud M; Ziauddin, Muhammed et al. (2011) Stereoselective vinylation of aryl N-(2-pyridylsulfonyl) aldimines with 1-alkenyl-1,1-heterobimetallic reagents. Org Lett 13:6464-7
Cheng, Kevin; Carroll, Patrick J; Walsh, Patrick J (2011) Diasteroselective preparation of cyclopropanols using methylene bis(iodozinc). Org Lett 13:2346-9
Stanton, Gretchen R; Koz, Gamze; Walsh, Patrick J (2011) Highly diastereoselective chelation-controlled additions to ?-silyloxy ketones. J Am Chem Soc 133:7969-76
Valenta, Petr; Carroll, Patrick J; Walsh, Patrick J (2010) Stereoselective synthesis of ?-hydroxy enamines, aminocyclopropanes, and 1,3-amino alcohols via asymmetric catalysis. J Am Chem Soc 132:14179-90
Stanton, Gretchen R; Johnson, Corinne N; Walsh, Patrick J (2010) Overriding Felkin control: a general method for highly diastereoselective chelation-controlled additions to alpha-silyloxy aldehydes. J Am Chem Soc 132:4399-408
Kim, Hun Young; Salvi, Luca; Carroll, Patrick J et al. (2010) One-pot catalytic enantio- and diastereoselective syntheses of anti-, syn-cis-disubstituted, and syn-vinyl cyclopropyl alcohols. J Am Chem Soc 132:402-12

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