Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM059426-05S1
Application #
6879244
Study Section
Medicinal Chemistry Study Section (MCHA)
Program Officer
Schwab, John M
Project Start
2000-03-01
Project End
2006-02-28
Budget Start
2004-04-01
Budget End
2005-02-28
Support Year
5
Fiscal Year
2004
Total Cost
$44,198
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Zhai, Feng; Bukhryakov, Konstantin V; Schrock, Richard R et al. (2018) Syntheses of Molybdenum Oxo Benzylidene Complexes. J Am Chem Soc 140:13609-13613
Bukhryakov, Konstantin V; Schrock, Richard R; Hoveyda, Amir H et al. (2018) Syntheses of Molybdenum Oxo Alkylidene Complexes through Addition of Water to an Alkylidyne Complex. J Am Chem Soc 140:2797-2800
Kang, Taek; White, Kolby L; Mann, Tyler J et al. (2017) Enantioselective Total Synthesis of (-)-Deoxoapodine. Angew Chem Int Ed Engl 56:13857-13860
Nguyen, Thach T; Koh, Ming Joo; Mann, Tyler J et al. (2017) Synthesis of E- and Z-trisubstituted alkenes by catalytic cross-metathesis. Nature 552:347-354
Bukhryakov, Konstantin V; Schrock, Richard R; Hoveyda, Amir H et al. (2017) Synthesis of 2,6-Hexa-tert-butylterphenyl Derivatives, 2,6-(2,4,6-t-Bu3C6H2)2C6H3X, where X = I, Li, OH, SH, N3, or NH2. Org Lett 19:2607-2609
Shen, Xiao; Nguyen, Thach T; Koh, Ming Joo et al. (2017) Kinetically E-selective macrocyclic ring-closing metathesis. Nature 541:380-385
van der Mei, Farid W; Qin, Changming; Morrison, Ryan J et al. (2017) Practical, Broadly Applicable, ?-Selective, Z-Selective, Diastereoselective, and Enantioselective Addition of Allylboron Compounds to Mono-, Di-, Tri-, and Polyfluoroalkyl Ketones. J Am Chem Soc 139:9053-9065
Koh, Ming Joo; Nguyen, Thach T; Lam, Jonathan K et al. (2017) Molybdenum chloride catalysts for Z-selective olefin metathesis reactions. Nature 542:80-85
van der Mei, Farid W; Miyamoto, Hiroshi; Silverio, Daniel L et al. (2016) Lewis Acid Catalyzed Borotropic Shifts in the Design of Diastereo- and Enantioselective ?-Additions of Allylboron Moieties to Aldimines. Angew Chem Int Ed Engl 55:4701-6
Yu, Elsie C; Johnson, Brett M; Townsend, Erik M et al. (2016) Synthesis of Linear (Z)-?,?-Unsaturated Esters by Catalytic Cross-Metathesis. The Influence of Acetonitrile. Angew Chem Int Ed Engl 55:13210-13214

Showing the most recent 10 out of 74 publications