Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM060494-05S1
Application #
6895701
Study Section
Cell Development and Function Integrated Review Group (CDF)
Program Officer
Deatherage, James F
Project Start
2000-01-01
Project End
2008-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
5
Fiscal Year
2004
Total Cost
$6,819
Indirect Cost
Name
Washington University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Lenartowska, Marta; Isaji, Mamiko; Miller, Kathryn G (2012) A pre-embedding immunogold approach reveals localization of myosin VI at the ultrastructural level in the actin cones that mediate Drosophila spermatid individualization. Protoplasma 249:337-46
Isaji, Mamiko; Lenartowska, Marta; Noguchi, Tatsuhiko et al. (2011) Myosin VI regulates actin structure specialization through conserved cargo-binding domain sites. PLoS One 6:e22755
Noguchi, Tatsuhiko; Frank, Deborah J; Isaji, Mamiko et al. (2009) Coiled-coil-mediated dimerization is not required for myosin VI to stabilize actin during spermatid individualization in Drosophila melanogaster. Mol Biol Cell 20:358-67
Noguchi, Tatsuhiko; Lenartowska, Marta; Rogat, Aaron D et al. (2008) Proper cellular reorganization during Drosophila spermatid individualization depends on actin structures composed of two domains, bundles and meshwork, that are differentially regulated and have different functions. Mol Biol Cell 19:2363-72
Morrison, Julie K; Miller, Kathryn G (2008) Genetic characterization of the Drosophila jaguar322 mutant reveals that complete myosin VI loss of function is not lethal. Genetics 179:711-6
Frank, Deborah J; Martin, Stephen R; Gruender, Bridget N T et al. (2006) Androcam is a tissue-specific light chain for myosin VI in the Drosophila testis. J Biol Chem 281:24728-36
Noguchi, Tatsuhiko; Lenartowska, Marta; Miller, Kathryn G (2006) Myosin VI stabilizes an actin network during Drosophila spermatid individualization. Mol Biol Cell 17:2559-71
Rogat, Aaron D; Miller, Kathryn G (2002) A role for myosin VI in actin dynamics at sites of membrane remodeling during Drosophila spermatogenesis. J Cell Sci 115:4855-65