In sum, overall the project suffered an estimated 3 month set-back. We have requested supplementary funding for 3 months (25% of the current years direct cost award of $192,456 or $48,144) to cover this set-back. The primary request is to recoup salary associated with lost time (postdocs and PI salary) and a small amount to offset the cost of reagents and lab supplies required to recover experiments that were on-going at the time of the storm and to replace reagents for future use. Please see budget justification for additional details.
Germ cells are the link from generation to generation and must proliferate to ensure fertility; and germ cell proliferation is controlled by interaction with neighboring cells and by hormones and nutrition. We study conserved molecular pathways that control germ cell proliferation. These investigations inform similar processes in humans with implications for fertility; cancer; and stem cell biology.
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