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Wilson, Christopher J; Das, Madhurima; Jayaraman, Shobini et al. (2018) Effects of Disease-Causing Mutations on the Conformation of Human Apolipoprotein A-I in Model Lipoproteins. Biochemistry 57:4583-4596
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Klimtchuk, Elena S; Prokaeva, Tatiana; Frame, Nicholas M et al. (2018) Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease. Proc Natl Acad Sci U S A 115:E6428-E6436
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Jayaraman, Shobini; Gantz, Donald L; Haupt, Christian et al. (2018) Serum amyloid A sequesters diverse phospholipids and their hydrolytic products, hampering fibril formation and proteolysis in a lipid-dependent manner. Chem Commun (Camb) 54:3532-3535
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Frame, Nicholas M; Gursky, Olga (2017) Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks. Amyloid 24:13-14
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Das, Madhurima; Wilson, Christopher J; Mei, Xiaohu et al. (2017) Structural stability and local dynamics in disease-causing mutants of human apolipoprotein a-I: what makes the protein amyloidogenic? Amyloid 24:11-12
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Jayaraman, Shobini; Sánchez-Quesada, Jose Luis; Gursky, Olga (2017) Triglyceride increase in the core of high-density lipoproteins augments apolipoprotein dissociation from the surface: Potential implications for treatment of apolipoprotein deposition diseases. Biochim Biophys Acta Mol Basis Dis 1863:200-210
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Jayaraman, Shobini; Gantz, Donald L; Haupt, Christian et al. (2017) Serum amyloid A forms stable oligomers that disrupt vesicles at lysosomal pH and contribute to the pathogenesis of reactive amyloidosis. Proc Natl Acad Sci U S A 114:E6507-E6515
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Frame, Nicholas M; Jayaraman, Shobini; Gantz, Donald L et al. (2017) Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a ""molecular mop"" in immune response. J Struct Biol 200:293-302
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Madico, Guillermo; Gursky, Olga; Fairman, Jeff et al. (2017) Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens. Vaccines (Basel) 6:
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Prokaeva, Tatiana; Akar, Harun; Spencer, Brian et al. (2017) Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant. Kidney Int Rep 2:1223-1232
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