Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD013938-17
Application #
2197046
Study Section
Biochemical Endocrinology Study Section (BCE)
Program Officer
Yoshinaga, Koji
Project Start
1979-09-01
Project End
1998-01-31
Budget Start
1995-02-01
Budget End
1998-01-31
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Albany Medical College
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Albany
State
NY
Country
United States
Zip Code
12208
Alouf, C A; Reichert Jr, L E; Kellom, T A et al. (1997) Cultured human granulosa cells secrete a follicle stimulating hormone receptor-binding inhibitor. Hum Reprod 12:2735-40
Grasso, P; Rozhavskaya, M; Reichert Jr, L E (1997) A synthetic peptide corresponding to amino acid residues 34 to 37 of human follicle-stimulating hormone beta-subunit accelerates the onset of puberty in male and female mice. Endocrinology 138:4215-9
Grasso, P (1996) Functional reconstitution of detergent-solubilized bovine calf testis luteinizing hormone/chorionic gonadotropin receptor into phospholipid vesicles. Recept Signal Transduct 6:53-62
Grasso, P; Reichert Jr, L E (1996) In vivo effects of follicle-stimulating hormone-related synthetic peptides on the mouse estrous cycle. Endocrinology 137:5370-5
Grasso, P (1996) A synthetic peptide representing residues 7 to 21 of human luteinizing hormone beta-subunit binds calcium, facilitates calcium uptake by liposomes and possesses sequence similarity to calcium-binding domains of calmodulin. Regul Pept 65:109-14
Leng, N; Grasso, P; Reichert Jr, L E (1996) D-amino acid substitution of residues 32 to 46 of the glycoprotein hormone common alpha-subunit: development of a synthetic glycoprotein hormone antagonist. Pept Res 9:188-94
Grasso, P; Deziel, M R; Reichert Jr, L E (1995) Synthetic peptides corresponding to residues 551 to 555 and 650 to 653 of the rat testicular follicle-stimulating hormone (FSH) receptor are sufficient for post-receptor modulation of Sertoli cell responsiveness to FSH stimulation. Regul Pept 60:177-83
Grasso, P; Leng, N; Reichert Jr, L E (1995) A synthetic peptide corresponding to residues 645-653 in the carboxyl terminal cytoplasmic domain of the rat testicular follicle stimulating hormone receptor modulates G protein coupled-receptor signaling in rat testis membranes and in intact cultured rat Mol Cell Endocrinol 108:43-50
Leng, N; Dattatreyamurty, B; Reichert Jr, L E (1995) Identification of amino acid residues 300-315 of the rat FSH receptor as a hormone binding domain: evidence for its interaction with specific regions of FSH beta-subunit. Biochem Biophys Res Commun 210:392-9
Grasso, P; Deziel, M R; Reichert Jr, L E (1995) Selective effects of charge on G protein activation by FSH-receptor residues 551-555 and 650-653. Pept Res 8:278-84

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