Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD015045-11S2
Application #
3312949
Study Section
Reproductive Biology Study Section (REB)
Project Start
1980-09-01
Project End
1995-05-31
Budget Start
1993-06-01
Budget End
1994-05-31
Support Year
11
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Sapiro, Rossana; Kostetskii, Igor; Olds-Clarke, Patricia et al. (2002) Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6. Mol Cell Biol 22:6298-305
Si, Y; Olds-Clarke, P (2000) Evidence for the involvement of calmodulin in mouse sperm capacitation. Biol Reprod 62:1231-9
Redkar, A A; Si, Y; Twine, S N et al. (2000) Genes in the first and fourth inversions of the mouse t complex synergistically mediate sperm capacitation and interactions with the oocyte. Dev Biol 226:267-80
Redkar, A A; Olds-Clarke, P J (1999) An improved mouse sperm-oocyte plasmalemma binding assay: studies on characteristics of sperm binding in medium with or without glucose. J Androl 20:500-8
Si, Y; Olds-Clarke, P (1999) Mice carrying two t haplotypes: sperm populations with reduced Zona pellucida binding are deficient in capacitation. Biol Reprod 61:305-11
Redkar, A A; Olds-Clarke, P; Dugan, L M et al. (1998) High-resolution mapping of sperm function defects in the t complex fourth inversion. Mamm Genome 9:825-30
Harrison, A; Olds-Clarke, P; King, S M (1998) Identification of the t complex-encoded cytoplasmic dynein light chain tctex1 in inner arm I1 supports the involvement of flagellar dyneins in meiotic drive. J Cell Biol 140:1137-47
Visconti, P E; Olds-Clarke, P; Moss, S B et al. (1996) Properties and localization of a tyrosine phosphorylated form of hexokinase in mouse sperm. Mol Reprod Dev 43:82-93
Visconti, P E; Moore, G D; Bailey, J L et al. (1995) Capacitation of mouse spermatozoa. II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway. Development 121:1139-50
Visconti, P E; Bailey, J L; Moore, G D et al. (1995) Capacitation of mouse spermatozoa. I. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 121:1129-37

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