Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD017691-07
Application #
3314709
Study Section
Molecular Biology Study Section (MBY)
Project Start
1983-04-01
Project End
1989-07-31
Budget Start
1989-04-01
Budget End
1989-07-31
Support Year
7
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Brandeis University
Department
Type
Schools of Arts and Sciences
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Copeland, P R; Wormington, M (2001) The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN. RNA 7:875-86
Brzostowski, J; Robinson, C; Orford, R et al. (2000) RNA-dependent cytoplasmic anchoring of a transcription factor subunit during Xenopus development. EMBO J 19:3683-93
Korner, C G; Wormington, M; Muckenthaler, M et al. (1998) The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes. EMBO J 17:5427-37
Meric, F; Searfoss, A M; Wormington, M et al. (1996) Masking and unmasking maternal mRNA. The role of polyadenylation, transcription, splicing, and nuclear history. J Biol Chem 271:30804-10
Wormington, M; Searfoss, A M; Hurney, C A (1996) Overexpression of poly(A) binding protein prevents maturation-specific deadenylation and translational inactivation in Xenopus oocytes. EMBO J 15:900-9
Wormington, M (1993) Poly(A) and translation: development control. Curr Opin Cell Biol 5:950-4
Varnum, S M; Hurney, C A; Wormington, W M (1992) Maturation-specific deadenylation in Xenopus oocytes requires nuclear and cytoplasmic factors. Dev Biol 153:283-90
Wormington, M (1991) Preparation of synthetic mRNAs and analyses of translational efficiency in microinjected Xenopus oocytes. Methods Cell Biol 36:167-83
Keiper, B D; Wormington, W M (1990) Nucleotide sequence and 40 S subunit assembly of Xenopus laevis ribosomal protein S22. J Biol Chem 265:19397-400
Varnum, S M; Wormington, W M (1990) Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control. Genes Dev 4:2278-86

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