Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD019593-02S1
Application #
3316985
Study Section
Human Embryology and Development Subcommittee 2 (HED)
Project Start
1986-04-01
Project End
1989-11-30
Budget Start
1986-04-01
Budget End
1986-11-30
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Sadler, T W (1997) Mouse embryos in culture: models for understanding diabetes-induced embryopathies and gene function. Int J Dev Biol 41:291-7
Peet, J H; Sadler, T W (1996) Mouse embryonic cardiac metabolism under euglycemic and hypoglycemic conditions. Teratology 54:20-6
Perfetti, R; Raygada, M; Wang, Y et al. (1996) Regenerating (reg) and insulin genes are expressed in prepancreatic mouse embryos. J Mol Endocrinol 17:79-88
Buchanan, T A; Denno, K M; Sipos, G F et al. (1994) Diabetic teratogenesis. In vitro evidence for a multifactorial etiology with little contribution from glucose per se. Diabetes 43:656-60
Denno, K M; Sadler, T W (1994) Effects of the biguanide class of oral hypoglycemic agents on mouse embryogenesis. Teratology 49:260-6
Sadler, T W; Denno, K M; Hunter 3rd, E S (1993) Effects of altered maternal metabolism during gastrulation and neurulation stages of embryogenesis. Ann N Y Acad Sci 678:48-61
Sulik, K K; Sadler, T W (1993) Postulated mechanisms underlying the development of neural tube defects. Insights from in vitro and in vivo studies. Ann N Y Acad Sci 678:8-21
Hunter 3rd, E S; Sadler, T W (1992) The role of the visceral yolk sac in hyperglycemia-induced embryopathies in mouse embryos in vitro. Teratology 45:195-203
Hunter 3rd, E S; Phillips, L S; Goldstein, S et al. (1991) Altered visceral yolk sac function produced by a low-molecular-weight somatomedin inhibitor. Teratology 43:331-40
Shum, L; Sadler, T W (1991) Recovery by mouse embryos following teratogenic exposure to ketosis. Diabetologia 34:289-95

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