Pituitary Gonadotropin Gene Regulation

Mellon, Pamela L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Research Project (R01)
• Project #: 3R01HD020377-08S1
• Application #: 3318394
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Project Start: 1992-01-01
• Project End: 1996-06-30
• Budget Start: 1992-03-01
• Budget End: 1992-06-30
• Support Year: 8
• Fiscal Year: 1992

Institution

• Name: University of California San Diego
• Type: Schools of Medicine
• DUNS #: 077758407
• City: La Jolla
• State: CA
• Country: United States
• Zip Code: 92093

Publications

Xie, Huimin; Hoffmann, Hanne M; Iyer, Anita K et al. (2017) Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. Reprod Biol Endocrinol 15:86

Xie, Huimin; Hoffmann, Hanne M; Meadows, Jason D et al. (2015) Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development. Mol Endocrinol 29:842-55

Glidewell-Kenney, Christine A; Trang, Crystal; Shao, Paul P et al. (2014) Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons. Endocrinology 155:3909-19

Hoffmann, Hanne M; Tamrazian, Anika; Xie, Huimin et al. (2014) Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology 155:4043-53

Roybal, Lacey L; Hambarchyan, Arpi; Meadows, Jason D et al. (2014) Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSH?. Mol Endocrinol 28:1640-55

Ahow, Maryse; Min, Le; Pampillo, Macarena et al. (2014) KISS1R signals independently of G?q/11 and triggers LH secretion via the ?-arrestin pathway in the male mouse. Endocrinology 155:4433-46

Witham, Emily A; Meadows, Jason D; Hoffmann, Hanne M et al. (2013) Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes. Mol Endocrinol 27:1283-94

Clark, Daniel D; Gorman, Michael R; Hatori, Megumi et al. (2013) Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6. J Biol Rhythms 28:15-25

Glidewell-Kenney, Christine A; Shao, Paul P; Iyer, Anita K et al. (2013) Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Mol Endocrinol 27:437-54

Xie, Huimin; Cherrington, Brian D; Meadows, Jason D et al. (2013) Msx1 homeodomain protein represses the ?GSU and GnRH receptor genes during gonadotrope development. Mol Endocrinol 27:422-36