Women who exercised and/or ate a low-glycemic diet and their offspring will be compared with matched women who did not exercise and/or ate a high-glycemic diet and their offspring. Evaluations (mothers and offspring) will include a lifestyle and medical questionnaire, a physical examination, a lipid profile, and assessment of body composition, fitness, cardiovascular function and insulin resistance.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD021268-18
Application #
6881238
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Program Officer
Signore, Caroline
Project Start
1986-04-01
Project End
2009-03-31
Budget Start
2005-04-01
Budget End
2009-03-31
Support Year
18
Fiscal Year
2005
Total Cost
$136,350
Indirect Cost
Name
Case Western Reserve University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Clapp 3rd, James F (2008) Long-term outcome after exercising throughout pregnancy: fitness and cardiovascular risk. Am J Obstet Gynecol 199:489.e1-6
Clapp, J F (2006) Influence of endurance exercise and diet on human placental development and fetal growth. Placenta 27:527-34
Jeffreys, R M; Stepanchak, W; Lopez, B et al. (2006) Uterine blood flow during supine rest and exercise after 28 weeks of gestation. BJOG 113:1239-47
Clapp 3rd, James F; Schmidt, Stephanie; Paranjape, Aditi et al. (2004) Maternal insulin-like growth factor-I levels (IGF-I) reflect placental mass and neonatal fat mass. Am J Obstet Gynecol 190:730-6
Bergmann, A; Zygmunt, M; Clapp 3rd, J F (2004) Running throughout pregnancy: effect on placental villous vascular volume and cell proliferation. Placenta 25:694-8
Clapp 3rd, James F (2003) The effects of maternal exercise on fetal oxygenation and feto-placental growth. Eur J Obstet Gynecol Reprod Biol 110 Suppl 1:S80-5
Clapp 3rd, James F; Little, Kathleen D; Widness, John A (2003) Effect of maternal exercise and fetoplacental growth rate on serum erythropoietin concentrations. Am J Obstet Gynecol 188:1021-5
Clapp 3rd, James F; Kim, Hyungjin; Burciu, Brindusa et al. (2002) Continuing regular exercise during pregnancy: effect of exercise volume on fetoplacental growth. Am J Obstet Gynecol 186:142-7
Clapp 3rd, James F (2002) Maternal carbohydrate intake and pregnancy outcome. Proc Nutr Soc 61:45-50
Clapp 3rd, J F; Kim, H; Burciu, B et al. (2000) Beginning regular exercise in early pregnancy: effect on fetoplacental growth. Am J Obstet Gynecol 183:1484-8

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