Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD021961-10
Application #
2198378
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1986-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Florida
Department
Veterinary Sciences
Type
Schools of Earth Sciences/Natur
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Heard, Melissa E; Melnyk, Stepan B; Simmen, Frank A et al. (2016) High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology 157:2870-82
Heard, Melissa E; Velarde, Michael C; Giudice, Linda C et al. (2015) Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod 92:140
Simmen, Rosalia C M; Heard, Melissa E; Simmen, Angela M et al. (2015) The Krüppel-like factors in female reproductive system pathologies. J Mol Endocrinol 54:R89-R101
Pabona, John Mark P; Zhang, Daying; Ginsburg, David S et al. (2015) Prolonged pregnancy in women is associated with attenuated myometrial expression of progesterone receptor co-regulator Krüppel-like Factor 9. J Clin Endocrinol Metab 100:166-74
Heard, Melissa E; Simmons, Christian D; Simmen, Frank A et al. (2014) Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis. Endocrinology 155:1532-46
Pabona, John Mark P; Simmen, Frank A; Nikiforov, Mikhail A et al. (2012) Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. J Clin Endocrinol Metab 97:E376-92
Heard, Melissa E; Pabona, John Mark P; Clayberger, Carol et al. (2012) The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus. Biol Reprod 87:115
Simmen, Frank A; Simmen, Rosalia C M (2011) The maternal womb: a novel target for cancer prevention in the era of the obesity pandemic? Eur J Cancer Prev 20:539-48
Simmons, Christian D; Pabona, John Mark P; Heard, Melissa E et al. (2011) Krüppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen. Biol Reprod 85:378-85
Pabona, John Mark P; Zeng, Zhaoyang; Simmen, Frank A et al. (2010) Functional differentiation of uterine stromal cells involves cross-regulation between bone morphogenetic protein 2 and Kruppel-like factor (KLF) family members KLF9 and KLF13. Endocrinology 151:3396-406

Showing the most recent 10 out of 16 publications