Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD029856-04
Application #
2202236
Study Section
Reproductive Biology Study Section (REB)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Psychiatry
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Lederman, Matthew A; Lebesgue, Diane; Gonzalez, Veronica V et al. (2010) Age-related LH surge dysfunction correlates with reduced responsiveness of hypothalamic anteroventral periventricular nucleus kisspeptin neurons to estradiol positive feedback in middle-aged rats. Neuropharmacology 58:314-20
Todd, Brigitte J; Merhi, Zaher O; Shu, Jun et al. (2010) Hypothalamic insulin-like growth factor-I receptors are necessary for hormone-dependent luteinizing hormone surges: implications for female reproductive aging. Endocrinology 151:1356-66
Buyuk, Erkan; Nejat, Edward; Neal-Perry, Genevieve (2010) Determinants of female reproductive senescence: differential roles for the ovary and the neuroendocrine axis. Semin Reprod Med 28:370-9
Neal-Perry, Genevieve; Lebesgue, Diane; Lederman, Matthew et al. (2009) The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats. Endocrinology 150:3699-708
Neal-Perry, Genevieve S; Zeevalk, Gail D; Shu, Jun et al. (2008) Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area. Biol Reprod 79:878-88
Reyna-Neyra, A; Sarkar, G; Etgen, A M (2007) Regulation of soluble guanylyl cyclase activity by oestradiol and progesterone in the hypothalamus but not hippocampus of female rats. J Neuroendocrinol 19:418-25
Todd, Brigitte J; Fraley, Gregory S; Peck, Alison C et al. (2007) Central insulin-like growth factor 1 receptors play distinct roles in the control of reproduction, food intake, and body weight in female rats. Biol Reprod 77:492-503
Acosta-Martinez, Maricedes; Gonzalez-Flores, Oscar; Etgen, Anne M (2006) The role of progestin receptors and the mitogen-activated protein kinase pathway in delta opioid receptor facilitation of female reproductive behaviors. Horm Behav 49:458-62
Etgen, Anne M; Gonzalez-Flores, Oscar; Todd, Brigitte J (2006) The role of insulin-like growth factor-I and growth factor-associated signal transduction pathways in estradiol and progesterone facilitation of female reproductive behaviors. Front Neuroendocrinol 27:363-75
Knuth, Emily D; Etgen, Anne M (2005) Corticosterone secretion induced by chronic isolation in neonatal rats is sexually dimorphic and accompanied by elevated ACTH. Horm Behav 47:65-75

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