Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD031579-01S1
Application #
2204197
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1994-05-01
Budget End
1995-04-30
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Stanford University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Nyegaard, Mette; Overgaard, Michael T; Su, You-Qiang et al. (2010) Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility. Biol Reprod 82:1129-38
Kwintkiewicz, Jakub; Nishi, Yoshihiro; Yanase, Toshihiko et al. (2010) Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells. Environ Health Perspect 118:400-6
Kwintkiewicz, Jakub; Giudice, Linda C (2009) The interplay of insulin-like growth factors, gonadotropins, and endocrine disruptors in ovarian follicular development and function. Semin Reprod Med 27:43-51
Su, You-Qiang; Nyegaard, Mette; Overgaard, Michael Toft et al. (2006) Participation of mitogen-activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles. Biol Reprod 75:859-67
Giudice, Linda C (2006) Endometrium in PCOS: Implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab 20:235-44
Glerup, Simon; Boldt, Henning B; Overgaard, Michael T et al. (2005) Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements. J Biol Chem 280:9823-32
Weyer, Kathrin; Overgaard, Michael T; Laursen, Lisbeth S et al. (2004) Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. Eur J Biochem 271:1525-35
Overgaard, Michael T; Glerup, Simon; Boldt, Henning B et al. (2004) Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase. FEBS Lett 560:147-52
Boldt, Henning B; Kjaer-Sorensen, Kasper; Overgaard, Michael T et al. (2004) The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity. J Biol Chem 279:38525-31
Imani, Babak; Eijkemans, Marinus J C; Faessen, Gerry H et al. (2002) Prediction of the individual follicle-stimulating hormone threshold for gonadotropin induction of ovulation in normogonadotropic anovulatory infertility: an approach to increase safety and efficiency. Fertil Steril 77:83-90

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