Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD035920-07
Application #
6707552
Study Section
Cell Development and Function Integrated Review Group (CDF)
Program Officer
Javois, Lorette Claire
Project Start
1999-01-01
Project End
2008-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
7
Fiscal Year
2004
Total Cost
$298,080
Indirect Cost
Name
University of Georgia
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
004315578
City
Athens
State
GA
Country
United States
Zip Code
30602
Manley, Nancy Ruth; Richie, Ellen Rothman; Blackburn, Catherine Clare et al. (2011) Structure and function of the thymic microenvironment. Front Biosci (Landmark Ed) 16:2461-77
Liu, Zhijie; Farley, Alison; Chen, Lizhen et al. (2010) Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genet 6:e1001251
Gordon, Julie; Patel, Seema R; Mishina, Yuji et al. (2010) Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Dev Biol 339:141-54
Griffith, Ann V; Cardenas, Kim; Carter, Carla et al. (2009) Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos. Dev Biol 327:216-27
Liu, Zhijie; Yu, Shannon; Manley, Nancy R (2007) Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol 305:333-46
Gordon, Julie; Xiao, Shiyun; Hughes 3rd, Bernard et al. (2007) Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol 7:69
Patel, Seema R; Gordon, Julie; Mahbub, Farah et al. (2006) Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expr Patterns 6:794-9
Moore-Scott, Billie A; Manley, Nancy R (2005) Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev Biol 278:323-35
Manley, Nancy R; Selleri, Licia; Brendolan, Andrea et al. (2004) Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol 276:301-12
Gordon, Julie; Wilson, Valerie A; Blair, Natalie F et al. (2004) Functional evidence for a single endodermal origin for the thymic epithelium. Nat Immunol 5:546-53

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