Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD039963-06
Application #
6627413
Study Section
Reproductive Biology Study Section (REB)
Program Officer
Taymans, Susan
Project Start
1998-01-01
Project End
2005-12-31
Budget Start
2003-01-01
Budget End
2003-12-31
Support Year
6
Fiscal Year
2003
Total Cost
$207,900
Indirect Cost
Name
Duke University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Garcia-Moreno, S Alexandra; Plebanek, Michael P; Capel, Blanche (2018) Epigenetic regulation of male fate commitment from an initially bipotential system. Mol Cell Endocrinol 468:19-30
Maatouk, Danielle M; Natarajan, Anirudh; Shibata, Yoichiro et al. (2017) Genome-wide identification of regulatory elements in Sertoli cells. Development 144:720-730
DeFalco, Tony; Potter, Sarah J; Williams, Alyna V et al. (2015) Macrophages Contribute to the Spermatogonial Niche in the Adult Testis. Cell Rep 12:1107-19
Lin, Yi-Tzu; Capel, Blanche (2015) Cell fate commitment during mammalian sex determination. Curr Opin Genet Dev 32:144-52
DeFalco, Tony; Bhattacharya, Indrashis; Williams, Alyna V et al. (2014) Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis. Proc Natl Acad Sci U S A 111:E2384-93
Munger, Steven C; Natarajan, Anirudh; Looger, Loren L et al. (2013) Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination. PLoS Genet 9:e1003630
Defalco, Tony; Saraswathula, Anirudh; Briot, Anaïs et al. (2013) Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling. Biol Reprod 88:91
Garcia, Thomas Xavier; DeFalco, Tony; Capel, Blanche et al. (2013) Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol 377:188-201
Maatouk, Danielle M; Mork, Lindsey; Chassot, Anne-Amandine et al. (2013) Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary. Dev Biol 383:295-306
Mork, Lindsey; Tang, Hao; Batchvarov, Iordan et al. (2012) Mouse germ cell clusters form by aggregation as well as clonal divisions. Mech Dev 128:591-6

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