Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD046737-01S1
Application #
6952598
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Program Officer
Ilekis, John V
Project Start
2004-04-01
Project End
2009-01-31
Budget Start
2004-04-01
Budget End
2005-01-31
Support Year
1
Fiscal Year
2004
Total Cost
$118,875
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Tsai, Yu-Cheng; Cooke, Nancy E; Liebhaber, Stephen A (2014) Tissue specific CTCF occupancy and boundary function at the human growth hormone locus. Nucleic Acids Res 42:4906-21
Ho, Yugong; Shewchuk, Brian M; Liebhaber, Stephen A et al. (2013) Distinct chromatin configurations regulate the initiation and the maintenance of hGH gene expression. Mol Cell Biol 33:1723-34
Ho, Yugong; Liebhaber, Stephen A; Cooke, Nancy E (2011) The role of the hGH locus control region in somatotrope restriction of hGH-N gene expression. Mol Endocrinol 25:877-84
Sizova, Daria; Ho, Yugong; Cooke, Nancy E et al. (2010) Research resource: T-antigen transformation of pituitary cells captures three novel cell lines in the Pit-1 lineage. Mol Endocrinol 24:2232-40
Ho, Yugong; Tadevosyan, Aleksey; Liebhaber, Stephen A et al. (2008) The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression. EMBO Rep 9:891-8
Kimura, Atsushi P; Sizova, Daria; Handwerger, Stuart et al. (2007) Epigenetic activation of the human growth hormone gene cluster during placental cytotrophoblast differentiation. Mol Cell Biol 27:6555-68
Yoo, Eung Jae; Cajiao, Isabela; Kim, Jeong-Seon et al. (2006) Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions. Mol Cell Biol 26:5569-79