Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL002212-40A3
Application #
2209910
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1974-10-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
40
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Anatomy/Cell Biology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Hang, Jun; Zemskov, Evgeny A; Lorand, Laszlo et al. (2005) Identification of a novel recognition sequence for fibronectin within the NH2-terminal beta-sandwich domain of tissue transglutaminase. J Biol Chem 280:23675-83
Murthy, S N Prasanna; Iismaa, Siiri; Begg, Gillian et al. (2002) Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity. Proc Natl Acad Sci U S A 99:2738-42
Lorand, L (2001) Factor XIII: structure, activation, and interactions with fibrinogen and fibrin. Ann N Y Acad Sci 936:291-311
Murthy, S N; Lorand, L (2000) Nucleotide binding by the erythrocyte transglutaminase/Gh protein, probed with fluorescent analogs of GTP and GDP. Proc Natl Acad Sci U S A 97:7744-7
Saber-Lichtenberg, Y; Brix, K; Schmitz, A et al. (2000) Covalent cross-linking of secreted bovine thyroglobulin by transglutaminase. FASEB J 14:1005-14
Lorand, L (2000) Sol Sherry Lecture in Thrombosis : research on clot stabilization provides clues for improving thrombolytic therapies. Arterioscler Thromb Vasc Biol 20:9-Feb
Murthy, S N; Wilson, J H; Lukas, T J et al. (2000) Transglutaminase-catalyzed crosslinking of the Aalpha and gamma constituent chains in fibrinogen. Proc Natl Acad Sci U S A 97:44-8
Murthy, S N; Lomasney, J W; Mak, E C et al. (1999) Interactions of G(h)/transglutaminase with phospholipase Cdelta1 and with GTP. Proc Natl Acad Sci U S A 96:11815-9
Lorand, L; Velasco, P T; Murthy, S N et al. (1999) Autoimmune antibody in a hemorrhagic patient interacts with thrombin-activated factor XIII in a unique manner. Blood 93:909-17
Murthy, S N; Wilson, J H; Lukas, T J et al. (1998) Cross-linking sites of the human tau protein, probed by reactions with human transglutaminase. J Neurochem 71:2607-14

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