Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL015728-20S1
Application #
3335039
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1976-05-01
Project End
1995-04-30
Budget Start
1992-05-01
Budget End
1993-04-30
Support Year
20
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Arts and Sciences
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Martinez, M B; Flickinger, M C; Nelsestuen, G L (1999) Steady-state enzyme kinetics in the Escherichia coli periplasm: a model of a whole cell biocatalyst. J Biotechnol 71:59-66
McDonald, J F; Nelsestuen, G L (1997) Potent inhibition of terminal complement assembly by clusterin: characterization of its impact on C9 polymerization. Biochemistry 36:7464-73
McDonald, J F; Shah, A M; Schwalbe, R A et al. (1997) Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site. Biochemistry 36:5120-7
McDonald, J F; Evans Jr, T C; Emeagwali, D B et al. (1997) Ionic properties of membrane association by vitamin K-dependent proteins: the case for univalency. Biochemistry 36:15589-98
Nelsestuen, G L; Martinez, M B (1997) Steady state enzyme velocities that are independent of [enzyme]: an important behavior in many membrane and particle-bound states. Biochemistry 36:9081-6
Lu, Y; Nelsestuen, G L (1996) Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: implications for protein--membrane contact. Biochemistry 35:8193-200
Lu, Y; Nelsestuen, G L (1996) The prothrombinase reaction: ""mechanism switching"" between Michaelis-Menten and non-Michaelis-Menten behaviors. Biochemistry 35:8201-9
Evans Jr, T C; Nelsestuen, G L (1996) Importance of cis-proline 22 in the membrane-binding conformation of bovine prothrombin. Biochemistry 35:8210-5
Martinez, M B; Flickinger, M C; Nelsestuen, G L (1996) Accurate kinetic modeling of alkaline phosphatase in the Escherichia coli periplasm: implications for enzyme properties and substrate diffusion. Biochemistry 35:1179-86
Schwalbe, R A; Coe, J E; Nelsestuen, G L (1995) Association of rat C-reactive protein and other pentraxins with rat lipoproteins containing apolipoproteins E and A1. Biochemistry 34:10432-9

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