Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL016919-25
Application #
6109412
Study Section
Project Start
1998-09-01
Project End
1999-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
25
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Black, Peter C; Mize, Gregory J; Karlin, Peter et al. (2007) Overexpression of protease-activated receptors-1,-2, and-4 (PAR-1, -2, and -4) in prostate cancer. Prostate 67:743-56
Kulman, John D; Satake, Masanobu; Harris, Jeff E (2007) A versatile system for site-specific enzymatic biotinylation and regulated expression of proteins in cultured mammalian cells. Protein Expr Purif 52:320-8
Kulman, John D; Harris, Jeff E; Xie, Ling et al. (2007) Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein. Proc Natl Acad Sci U S A 104:8767-72
Davie, Earl W; Kulman, John D (2006) An overview of the structure and function of thrombin. Semin Thromb Hemost 32 Suppl 1:3-15
Kulman, John D; Harris, Jeff E; Nakazawa, Noriko et al. (2006) Vitamin K-dependent proteins in Ciona intestinalis, a basal chordate lacking a blood coagulation cascade. Proc Natl Acad Sci U S A 103:15794-9
Pratt, Kathleen P; Qian, Jiahua; Ellaban, Ekram et al. (2004) Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site. Thromb Haemost 92:522-8
Takeshima, Kazuya; Smith, Christina; Tait, Jonathan et al. (2003) The preparation and phospholipid binding property of the C2 domain of human factor VIII. Thromb Haemost 89:788-94
Greenberg, Daniel L; Mize, Gregory J; Takayama, Thomas K (2003) Protease-activated receptor mediated RhoA signaling and cytoskeletal reorganization in LNCaP cells. Biochemistry 42:702-9
Chung, Dominic W; Fujikawa, Kazuo (2002) Processing of von Willebrand factor by ADAMTS-13. Biochemistry 41:11065-70
Fuentes-Prior, Pablo; Fujikawa, Kazuo; Pratt, Kathleen P (2002) New insights into binding interfaces of coagulation factors V and VIII and their homologues lessons from high resolution crystal structures. Curr Protein Pept Sci 3:313-39

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