The overall objective of this project is to explore the capabilities of new ultrasonic techniques to non-invasively evaluate and quantitate atherosclerotic plaques and their effects on the circulation of the blood. We will utilize non-invasive, surgical and x-ray arteriographic techniques and explore the direct and indirect effects of plaquing with continuous-wave Doppler, pulsed wave Doppler, and combinations thereof with the utilization of frequency spectral analysis and will utilize high resolution B-scan ultrasonic imaging. Human subjects will be primarily utilized, but some in vitro modeling will be used.
| Thomas, G I; Jones, T W; Stavney, L S et al. (1986) Carotid endarterectomy after Doppler ultrasonographic examination without angiography. Am J Surg 151:616-9 |
| Faccenda, F; Usui, Y; Spencer, M P (1985) Doppler measurement of the pressure drop caused by arterial stenosis: an experimental study: a case report. Angiology 36:899-905 |
