Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL020598-28
Application #
6691030
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Program Officer
Liang, Isabella Y
Project Start
1992-07-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
28
Fiscal Year
2004
Total Cost
$297,000
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Chen, Yingjie; Zhang, Ping; Li, Jingxin et al. (2014) Inducible nitric oxide synthase inhibits oxygen consumption in collateral-dependent myocardium. Am J Physiol Heart Circ Physiol 306:H356-62
Zhang, Ping; Xu, Xin; Hu, Xinli et al. (2013) DDAH1 deficiency attenuates endothelial cell cycle progression and angiogenesis. PLoS One 8:e79444
Zhang, Ping; Hu, Xinli; Xu, Xin et al. (2011) Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt. Arterioscler Thromb Vasc Biol 31:890-7
Hu, Xinli; Atzler, Dorothee; Xu, Xin et al. (2011) Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler Thromb Vasc Biol 31:1540-6
Hu, Xinli; Xu, Xin; Lu, Zhongbing et al. (2011) AMP activated protein kinase-?2 regulates expression of estrogen-related receptor-?, a metabolic transcription factor related to heart failure development. Hypertension 58:696-703
Zhang, Ping; Hou, Mingxiao; Li, Yunfang et al. (2009) NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart. Am J Physiol Heart Circ Physiol 296:H840-6
Hu, Xinli; Xu, Xin; Huang, Yimin et al. (2008) Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload. Circ Res 103:1009-17
Liu, Zhenguo; Jiang, Yuehua; Hao, Hong et al. (2007) Endothelial nitric oxide synthase is dynamically expressed during bone marrow stem cell differentiation into endothelial cells. Am J Physiol Heart Circ Physiol 293:H1760-5
Traverse, Jay H; Chen, YingJie; Hou, MingXiao et al. (2007) Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure. Circ Res 100:1643-9
Traverse, Jay H; Nesmelov, Yuri E; Crampton, Melanie et al. (2006) Measurement of myocardial free radical production during exercise using EPR spectroscopy. Am J Physiol Heart Circ Physiol 290:H2453-8

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