Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL021872-19
Application #
2215508
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1978-02-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Wang, Huan; Hou, Lei; Kwak, Dongmin et al. (2016) Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression. Hypertension 68:114-22
Wang, Huan; Kwak, Dongmin; Fassett, John et al. (2016) CD28/B7 Deficiency Attenuates Systolic Overload-Induced Congestive Heart Failure, Myocardial and Pulmonary Inflammation, and Activated T Cell Accumulation in the Heart and Lungs. Hypertension 68:688-96
Liu, Xiaoyu; Hou, Lei; Xu, Dachun et al. (2016) Effect of asymmetric dimethylarginine (ADMA) on heart failure development. Nitric Oxide 54:73-81
Liu, Xiaoyu; Kwak, Dongmin; Lu, Zhongbing et al. (2014) Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling. Hypertension 64:738-44
Lu, Zhongbing; Xu, Xin; Fassett, John et al. (2014) Loss of the eukaryotic initiation factor 2? kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy. Hypertension 63:128-35
Wang, Huan; Xu, Xin; Fassett, John et al. (2014) Double-stranded RNA-dependent protein kinase deficiency protects the heart from systolic overload-induced congestive heart failure. Circulation 129:1397-406
Chen, Yingjie; Zhang, Ping; Li, Jingxin et al. (2014) Inducible nitric oxide synthase inhibits oxygen consumption in collateral-dependent myocardium. Am J Physiol Heart Circ Physiol 306:H356-62
Xu, Xin; Lu, Zhongbing; Fassett, John et al. (2014) Metformin protects against systolic overload-induced heart failure independent of AMP-activated protein kinase ?2. Hypertension 63:723-8
Bache, Robert J; Chen, Yingjie (2014) NOX2-induced myocardial fibrosis and diastolic dysfunction: role of the endothelium. J Am Coll Cardiol 63:2742-4
Fassett, John T; Xu, Xin; Kwak, Dongmin et al. (2013) Microtubule Actin Cross-linking Factor 1 regulates cardiomyocyte microtubule distribution and adaptation to hemodynamic overload. PLoS One 8:e73887

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