Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL024111-17
Application #
2215717
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1987-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Michigan State University
Department
Pharmacology
Type
Schools of Osteopathy
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Xu, Hui; Fink, Gregory D; Galligan, James J (2007) Increased sympathetic venoconstriction and reactivity to norepinephrine in mesenteric veins in anesthetized DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol 293:H160-8
Xu, Hui; Jackson, William F; Fink, Gregory D et al. (2006) Activation of potassium channels by tempol in arterial smooth muscle cells from normotensive and deoxycorticosterone acetate-salt hypertensive rats. Hypertension 48:1080-7
Xu, Hui; Bian, Xiaochun; Watts, Stephanie W et al. (2005) Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats. Hypertension 46:1154-62
Xu, Hui; Fink, Gregory D; Galligan, James J (2004) Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats. Hypertension 43:329-34
Luo, Min; Hess, Margaret C; Fink, Gregory D et al. (2003) Differential alterations in sympathetic neurotransmission in mesenteric arteries and veins in DOCA-salt hypertensive rats. Auton Neurosci 104:47-57
Johnson, Ronald J; Fink, Gregory D; Watts, Stephanie W et al. (2002) Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats. J Hypertens 20:665-76
Xu, Hui; Fink, Gregory D; Galligan, James J (2002) Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in DOCA-salt rats. Am J Physiol Heart Circ Physiol 283:H885-92
Johnson, R J; Galligan, J J; Fink, G D (2001) Effect of an ET(B)-selective and a mixed ET(A/B) endothelin receptor antagonist on venomotor tone in deoxycorticosterone-salt hypertension. J Hypertens 19:431-40
Johnson, R J; Galligan, J J; Fink, G D (2001) Factors affecting endothelin-induced venous tone in conscious rats. J Cardiovasc Pharmacol 37:187-95
Ballew, J R; Fink, G D (2001) Role of endothelin ETB receptor activation in angiotensin II-induced hypertension: effects of salt intake. Am J Physiol Heart Circ Physiol 281:H2218-25

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