Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL024264-17
Application #
2215733
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1979-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Riley, D J; Thakker-Varia, S; Wilson, F J et al. (2000) Role of proteolysis and apoptosis in regression of pulmonary vascular remodeling. Physiol Res 49:577-85
Thakker-Varia, S; Tozzi, C A; Chari, S et al. (1999) Isolation of differentially expressed genes in hypertensive pulmonary artery of rats. Exp Lung Res 25:689-99
Thakker-Varia, S; Tozzi, C A; Poiani, G J et al. (1998) Expression of matrix-degrading enzymes in pulmonary vascular remodeling in the rat. Am J Physiol 275:L398-406
Tozzi, C A; Thakker-Varia, S; Yu, S Y et al. (1998) Mast cell collagenase correlates with regression of pulmonary vascular remodeling in the rat. Am J Respir Cell Mol Biol 18:497-510
Poiani, G J; Kemnitzer, J E; Fox, J D et al. (1997) Polymeric carrier of proline analogue with antifibrotic effect in pulmonary vascular remodeling. Am J Respir Crit Care Med 155:1384-90
Greco, M J; Kemnitzer, J E; Fox, J D et al. (1997) Polymer of proline analogue with sustained antifibrotic activity in lung fibrosis. Am J Respir Crit Care Med 155:1391-7
Laskin, D L; Soltys, R A; Berg, R A et al. (1994) Activation of alveolar macrophages by native and synthetic collagen-like polypeptides. Am J Respir Cell Mol Biol 10:58-64
Poiani, G J; Tozzi, C A; Thakker-Varia, S et al. (1994) Effect of glucocorticoids on collagen accumulation in pulmonary vascular remodeling in the rat. Am J Respir Crit Care Med 149:994-9
Poiani, G J; Greco, M; Choe, J K et al. (1994) Liposome encapsulation improves the effect of antifibrotic agent in rat lung fibrosis. Am J Respir Crit Care Med 150:1623-7
Tozzi, C A; Christiansen, D L; Poiani, G J et al. (1994) Excess collagen in hypertensive pulmonary arteries decreases vascular distensibility. Am J Respir Crit Care Med 149:1317-26

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