Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL025776-14
Application #
2215876
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1981-02-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Wilson, Jamie L; Warburton, Rod; Taylor, Linda et al. (2018) Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. PLoS One 13:e0195780
Wilson, Jamie L; Rupasinghe, Chamila; Usheva, Anny et al. (2015) Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides. Curr Top Pept Protein Res 16:1-17
Wilson, Jamie L; Yu, Jun; Taylor, Linda et al. (2015) Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK. PLoS One 10:e0123662
Yu, Jun; Wilson, Jamie; Taylor, Linda et al. (2015) DNA microarray and signal transduction analysis in pulmonary artery smooth muscle cells from heritable and idiopathic pulmonary arterial hypertension subjects. J Cell Biochem 116:386-97
Yu, Jun; Rupasinghe, Chamila; Wilson, Jamie L et al. (2015) Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chem Biol Drug Des 85:586-97
Yao, Chunxiang; Yu, Jun; Taylor, Linda et al. (2015) Protein Expression by Human Pulmonary Artery Smooth Muscle Cells Containing a BMPR2 Mutation and the Action of ET-1 as Determined by Proteomic Mass Spectrometry. Int J Mass Spectrom 378:347-359
Green, Daniel S; Rupasinghe, Chamila; Warburton, Rod et al. (2013) A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model. PLoS One 8:e81309
Yatawara, Achani; Wilson, Jamie L; Taylor, Linda et al. (2013) C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission. J Pept Sci 19:257-62
Yu, Jun; Taylor, Linda; Wilson, Jamie et al. (2013) Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. J Cell Physiol 228:322-9
Wilson, Jamie L; Taylor, Linda; Polgar, Peter (2012) Endothelin-1 activation of ETB receptors leads to a reduced cellular proliferative rate and an increased cellular footprint. Exp Cell Res 318:1125-33

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