Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL025942-14
Application #
2215937
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1988-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Michigan State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Rios-Steiner, Jorge L; Murakami, Mario T; Tulinsky, Alexander et al. (2007) Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum. J Mol Biol 371:774-86
Abad, Marta C; Arni, R K; Grella, Davida K et al. (2002) The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin. J Mol Biol 318:1009-17
Rios-Steiner, J L; Schenone, M; Mochalkin, I et al. (2001) Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein. J Mol Biol 308:705-19
St Charles, R; Padmanabhan, K; Arni, R V et al. (2000) Structure of tick anticoagulant peptide at 1.6 A resolution complexed with bovine pancreatic trypsin inhibitor. Protein Sci 9:265-72
Arni, R K; Padmanabhan, K P; Tulinsky, A (1999) Crystallization and preliminary diffraction data of a platelet-aggregation inhibitor from the venom of Agkistrodon piscivorus piscivorus (North American water moccasin). Acta Crystallogr D Biol Crystallogr 55:1468-70
Zhang, E; St Charles, R; Tulinsky, A (1999) Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant. J Mol Biol 285:2089-104
Mochalkin, I; Cheng, B; Klezovitch, O et al. (1999) Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry 38:1990-8
Chang, Y; Mochalkin, I; McCance, S G et al. (1998) Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen. Biochemistry 37:3258-71
Sabharwal, A K; Padmanabhan, K; Tulinsky, A et al. (1997) Interaction of calcium with native and decarboxylated human factor X. Effect of proteolysis in the autolysis loop on catalytic efficiency and factor Va binding. J Biol Chem 272:22037-45
Ganesh, V; Lee, A Y; Clardy, J et al. (1996) Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin. Protein Sci 5:825-35

Showing the most recent 10 out of 37 publications