Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL028448-15
Application #
2216290
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1981-06-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Lange, Yvonne; Ye, Jin; Steck, Theodore L (2014) Essentially all excess fibroblast cholesterol moves from plasma membranes to intracellular compartments. PLoS One 9:e98482
Lange, Yvonne; Tabei, S M Ali; Ye, Jin et al. (2013) Stability and stoichiometry of bilayer phospholipid-cholesterol complexes: relationship to cellular sterol distribution and homeostasis. Biochemistry 52:6950-9
Lange, Yvonne; Ye, Jin; Steck, Theodore L (2012) Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells. PLoS One 7:e30051
Steck, Theodore L; Lange, Yvonne (2010) Cell cholesterol homeostasis: mediation by active cholesterol. Trends Cell Biol 20:680-7
Lange, Yvonne; Ye, Jin; Duban, Mark-Eugene et al. (2009) Activation of membrane cholesterol by 63 amphipaths. Biochemistry 48:8505-15
Lange, Yvonne; Steck, Theodore L; Ye, Jin et al. (2009) Regulation of fibroblast mitochondrial 27-hydroxycholesterol production by active plasma membrane cholesterol. J Lipid Res 50:1881-8
Lange, Yvonne; Steck, Theodore L (2008) Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol. Prog Lipid Res 47:319-32
Lange, Yvonne; Ye, Jin; Steck, Theodore L (2007) Scrambling of phospholipids activates red cell membrane cholesterol. Biochemistry 46:2233-8