Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL030038-12
Application #
2216554
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1983-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Pharmacology
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Jollow, D J; McMillan, D C (2001) Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell. Adv Exp Med Biol 500:595-605
McMillan, D C; Jensen, C B; Jollow, D J (1998) Role of lipid peroxidation in dapsone-induced hemolytic anemia. J Pharmacol Exp Ther 287:868-76
Bradshaw, T P; McMillan, D C; Crouch, R K et al. (1997) Formation of free radicals and protein mixed disulfides in rat red cells exposed to dapsone hydroxylamine. Free Radic Biol Med 22:1183-93
Bradshaw, T P; McMillan, D C; Crouch, R K et al. (1995) Identification of free radicals produced in rat erythrocytes exposed to hemolytic concentrations of phenylhydroxylamine. Free Radic Biol Med 18:279-85
Grossman, S; Budinsky, R; Jollow, D (1995) Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone. J Pharmacol Exp Ther 273:870-7
McMillan, D C; Simson, J V; Budinsky, R A et al. (1995) Dapsone-induced hemolytic anemia: effect of dapsone hydroxylamine on sulfhydryl status, membrane skeletal proteins and morphology of human and rat erythrocytes. J Pharmacol Exp Ther 274:540-7
McMillan, D C; Schey, K L; Meier, G P et al. (1993) Chemical analysis and hemolytic activity of the fava bean aglycon divicine. Chem Res Toxicol 6:439-44
Grossman, S J; Simson, J; Jollow, D J (1992) Dapsone-induced hemolytic anemia: effect of N-hydroxy dapsone on the sulfhydryl status and membrane proteins of rat erythrocytes. Toxicol Appl Pharmacol 117:208-17
McMillan, D C; Bradshaw, T P; Hinson, J A et al. (1991) Role of metabolites in propanil-induced hemolytic anemia. Toxicol Appl Pharmacol 110:70-8
McMillan, D C; Bradshaw, T P; McMillan, J M et al. (1991) Contribution of 3,4-dichlorophenylhydroxylamine in propanil-induced hemolytic anemia. Adv Exp Med Biol 283:343-5

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