Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL031823-11
Application #
2216907
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1986-12-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Yang, Zhantao; Keel, Siobán B; Shimamura, Akiko et al. (2016) Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome. Sci Transl Med 8:338ra67
Philip, Mary; Chiu, Edison Y; Hajjar, Adeline M et al. (2016) TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages. J Immunol Res 2016:4039038
Egan, Daniel N; Yang, Zhantao; Phillips, John et al. (2015) Inducing iron deficiency improves erythropoiesis and photosensitivity in congenital erythropoietic porphyria. Blood 126:257-61
Doty, Raymond T; Phelps, Susan R; Shadle, Christina et al. (2015) Coordinate expression of heme and globin is essential for effective erythropoiesis. J Clin Invest 125:4681-91
Keel, Siobán B; Doty, Raymond; Liu, Li et al. (2015) Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver. Exp Hematol 43:469-78.e6
Philip, Mary; Funkhouser, Scott A; Chiu, Edison Y et al. (2015) Heme exporter FLVCR is required for T cell development and peripheral survival. J Immunol 194:1677-85
Byon, John C H; Chen, Jing; Doty, Raymond T et al. (2013) FLVCR is necessary for erythroid maturation, may contribute to platelet maturation, but is dispensable for normal hematopoietic stem cell function. Blood 122:2903-10
Keel, Sioban B; Phelps, Susan; Sabo, Kathleen M et al. (2012) Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis. Exp Hematol 40:290-4
Hromas, Robert; Abkowitz, Janis L; Keating, Armand (2012) Facing the NIH funding crisis: how professional societies can help. JAMA 308:2343-4
Jaacks, Lindsay M; Young, Melissa F; Essley, Bridget V et al. (2011) Placental expression of the heme transporter, feline leukemia virus subgroup C receptor, is related to maternal iron status in pregnant adolescents. J Nutr 141:1267-72

Showing the most recent 10 out of 41 publications