Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL033259-12
Application #
2028171
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1985-09-20
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Liao, Yung-Feng; Gotwals, Philip J; Koteliansky, Victor E et al. (2002) The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing. J Biol Chem 277:14467-74
Pittet, J F; Griffiths, M J; Geiser, T et al. (2001) TGF-beta is a critical mediator of acute lung injury. J Clin Invest 107:1537-44
Kaminski, N; Allard, J D; Pittet, J F et al. (2000) Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis. Proc Natl Acad Sci U S A 97:1778-83
Huang, X; Griffiths, M; Wu, J et al. (2000) Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice. Mol Cell Biol 20:755-9
Sheppard, D (2000) In vivo functions of integrins: lessons from null mutations in mice. Matrix Biol 19:203-9
Huang, X Z; Wu, J F; Ferrando, R et al. (2000) Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1. Mol Cell Biol 20:5208-15
Takahashi, H; Isobe, T; Horibe, S et al. (2000) Tissue transglutaminase, coagulation factor XIII, and the pro-polypeptide of von Willebrand factor are all ligands for the integrins alpha 9beta 1 and alpha 4beta 1. J Biol Chem 275:23589-95
Marcinkiewicz, C; Taooka, Y; Yokosaki, Y et al. (2000) Inhibitory effects of MLDG-containing heterodimeric disintegrins reveal distinct structural requirements for interaction of the integrin alpha 9beta 1 with VCAM-1, tenascin-C, and osteopontin. J Biol Chem 275:31930-7
Taooka, Y; Chen, J; Yednock, T et al. (1999) The integrin alpha9beta1 mediates adhesion to activated endothelial cells and transendothelial neutrophil migration through interaction with vascular cell adhesion molecule-1. J Cell Biol 145:413-20
Yokosaki, Y; Matsuura, N; Sasaki, T et al. (1999) The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem 274:36328-34

Showing the most recent 10 out of 43 publications