Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL034646-12A1
Application #
2217619
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1985-01-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Pathology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Libby, Peter (2003) Vascular biology of atherosclerosis: overview and state of the art. Am J Cardiol 91:3A-6A
Anderson, P G; Boerth, N J; Liu, M et al. (2000) Cyclic GMP-dependent protein kinase expression in coronary arterial smooth muscle in response to balloon catheter injury. Arterioscler Thromb Vasc Biol 20:2192-7
Komalavilas, P; Shah, P K; Jo, H et al. (1999) Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells. J Biol Chem 274:34301-9
Dey, N B; Boerth, N J; Murphy-Ullrich, J E et al. (1998) Cyclic GMP-dependent protein kinase inhibits osteopontin and thrombospondin production in rat aortic smooth muscle cells. Circ Res 82:139-46
Soff, G A; Cornwell, T L; Cundiff, D L et al. (1997) Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP. J Clin Invest 100:2580-7
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Komalavilas, P; Lincoln, T M (1996) Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta. J Biol Chem 271:21933-8
Murphy-Ullrich, J E; Pallero, M A; Boerth, N et al. (1996) Cyclic GMP-dependent protein kinase is required for thrombospondin and tenascin mediated focal adhesion disassembly. J Cell Sci 109 ( Pt 10):2499-508
Qian, Y; Chao, D S; Santillano, D R et al. (1996) cGMP-dependent protein kinase in dorsal root ganglion: relationship with nitric oxide synthase and nociceptive neurons. J Neurosci 16:3130-8
Pryzwansky, K B; Wyatt, T A; Lincoln, T M (1995) Cyclic guanosine monophosphate-dependent protein kinase is targeted to intermediate filaments and phosphorylates vimentin in A23187-stimulated human neutrophils. Blood 85:222-30

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