Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL034708-12
Application #
2691909
Study Section
Project Start
1995-12-01
Project End
1999-11-30
Budget Start
1997-12-01
Budget End
1998-11-30
Support Year
12
Fiscal Year
1998
Total Cost
Indirect Cost
Yang, MeiYing; Camara, Amadou K S; Aldakkak, Mohammed et al. (2017) Identity and function of a cardiac mitochondrial small conductance Ca2+-activated K+ channel splice variant. Biochim Biophys Acta Bioenerg 1858:442-458
Liu, Yanan; Yan, Yasheng; Inagaki, Yasuyoshi et al. (2017) Insufficient Astrocyte-Derived Brain-Derived Neurotrophic Factor Contributes to Propofol-Induced Neuron Death Through Akt/Glycogen Synthase Kinase 3?/Mitochondrial Fission Pathway. Anesth Analg 125:241-254
Sedlic, Filip; Muravyeva, Maria Y; Sepac, Ana et al. (2017) Targeted Modification of Mitochondrial ROS Production Converts High Glucose-Induced Cytotoxicity to Cytoprotection: Effects on Anesthetic Preconditioning. J Cell Physiol 232:216-24
Bosnjak, Zeljko J; Logan, Sarah; Liu, Yanan et al. (2016) Recent Insights Into Molecular Mechanisms of Propofol-Induced Developmental Neurotoxicity: Implications for the Protective Strategies. Anesth Analg 123:1286-1296
Canfield, Scott G; Zaja, Ivan; Godshaw, Brian et al. (2016) High Glucose Attenuates Anesthetic Cardioprotection in Stem-Cell-Derived Cardiomyocytes: The Role of Reactive Oxygen Species and Mitochondrial Fission. Anesth Analg 122:1269-79
Twaroski, Danielle; Bosnjak, Zeljko J; Bai, Xiaowen (2015) MicroRNAs: New Players in Anesthetic-Induced Developmental Neurotoxicity. Pharm Anal Acta 6:357
Kikuchi, Chika; Bienengraeber, Martin; Canfield, Scott et al. (2015) Comparison of Cardiomyocyte Differentiation Potential Between Type 1 Diabetic Donor- and Nondiabetic Donor-Derived Induced Pluripotent Stem Cells. Cell Transplant 24:2491-504
Twaroski, Danielle M; Yan, Yasheng; Zaja, Ivan et al. (2015) Altered Mitochondrial Dynamics Contributes to Propofol-induced Cell Death in Human Stem Cell-derived Neurons. Anesthesiology 123:1067-83
Olson, Jessica M; Yan, Yasheng; Bai, Xiaowen et al. (2015) Up-regulation of microRNA-21 mediates isoflurane-induced protection of cardiomyocytes. Anesthesiology 122:795-805
Zaja, Ivan; Bai, Xiaowen; Liu, Yanan et al. (2014) Cdk1, PKC? and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death. Biochem Biophys Res Commun 453:710-21

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