Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL035297-11
Application #
2217787
Study Section
Pathology A Study Section (PTHA)
Project Start
1988-12-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Petrovan, Ramona J; Yuan, Yuan; Curtiss, Linda K (2008) Expression of the Lyst(beige) mutation is atheroprotective in chow-fed apolipoprotein E-deficient mice. J Lipid Res 49:429-37
Mullick, Adam E; Soldau, Katrin; Kiosses, William B et al. (2008) Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events. J Exp Med 205:373-83
Petrovan, Ramona J; Kaplan, Charles D; Reisfeld, Ralph A et al. (2007) DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 27:1095-100
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Wiedmer, Therese; Zhao, Ji; Li, Lilin et al. (2004) Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proc Natl Acad Sci U S A 101:13296-301
Binder, Christoph J; Hartvigsen, Karsten; Chang, Mi-Kyung et al. (2004) IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest 114:427-37
Schiller, Natalie K; Black, Audrey S; Bradshaw, Gary P et al. (2004) Participation of macrophages in atherosclerotic lesion morphology in LDLr-/- mice. J Lipid Res 45:1398-409
Schiller, Natalie K; Boisvert, William A; Curtiss, Linda K (2002) Inflammation in atherosclerosis: lesion formation in LDL receptor-deficient mice with perforin and Lyst(beige) mutations. Arterioscler Thromb Vasc Biol 22:1341-6

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