The overall goal of the Framingham Children's Study (FCS) is to identify early childhood determinants of eating and exercise behaviors that relate to cardiovascular disease. The investigators have been following 100 families who are 3rd and 4th generation descendants of the original Framingham Heart Study cohort. The subjects were age 3-5 years at the onset of the study will be age 11-14 years at the beginning of the next grant cycle. There has been excellent cohort maintenance with over 90% of the original families continuing to participate. This revised application proposes to extend the FCS to permit the evaluation of the determinants of change in the child's risk behaviors and other risk factors from early childhood through puberty to mid to late teens, a time when the individual's risk profile should better reflect his/her cardiovascular risk status as an adult. The FCS is a longitudinal source of data on diet, activity and family and environmental factors in children. The investigators have collected extensive dietary data with an average of 32 days of diet records and almost 50 days of electronically monitored physical activity data for each subject. Additional data include psychosocial and anthropometric data on children and their parents. The extension of the FCS will allow continued monitoring of eating behaviors and physical activity habits of the children and their parents, as well as the personal environmental and behavioral factors influencing changes in the child's physical activity, diet, blood pressure, lipids and obesity from pre-school into the late teen years.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL035653-14
Application #
2702172
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1989-01-01
Project End
2001-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
14
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Boston University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Hasnain, Syed Ridda; Singer, Martha R; Bradlee, M Loring et al. (2014) Beverage intake in early childhood and change in body fat from preschool to adolescence. Child Obes 10:42-9
Moore, Lynn L; Singer, Martha R; Qureshi, M Mustafa et al. (2008) Dairy intake and anthropometric measures of body fat among children and adolescents in NHANES. J Am Coll Nutr 27:702-10
Moore, Lynn L; Bradlee, M Loring; Gao, Di et al. (2008) Effects of average childhood dairy intake on adolescent bone health. J Pediatr 153:667-73
Moore, Lynn L; Bradlee, M Loring; Gao, Di et al. (2006) Low dairy intake in early childhood predicts excess body fat gain. Obesity (Silver Spring) 14:1010-8
Moore, Lynn L; Singer, Martha R; Bradlee, M Loring et al. (2005) Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure change. Epidemiology 16:4-11
Proctor, M H; Moore, L L; Gao, D et al. (2003) Television viewing and change in body fat from preschool to early adolescence: The Framingham Children's Study. Int J Obes Relat Metab Disord 27:827-33
Moore, Lynn L; Gao, Di; Bradlee, M Loring et al. (2003) Does early physical activity predict body fat change throughout childhood? Prev Med 37:10-7
Hood, M Y; Moore, L L; Sundarajan-Ramamurti, A et al. (2000) Parental eating attitudes and the development of obesity in children. The Framingham Children's Study. Int J Obes Relat Metab Disord 24:1319-25
Moore, L L; Nguyen, U S; Rothman, K J et al. (1995) Preschool physical activity level and change in body fatness in young children. The Framingham Children's Study. Am J Epidemiol 142:982-8
Ellison, R C; Singer, M R; Moore, L L et al. (1995) Current caffeine intake of young children: amount and sources. J Am Diet Assoc 95:802-4

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