Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL036240-13
Application #
2874044
Study Section
Project Start
1996-09-01
Project End
1999-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
13
Fiscal Year
1998
Total Cost
Indirect Cost
Houle, M S; Altschuld, R A; Billman, G E (2001) Enhanced in vivo and in vitro contractile responses to beta(2)-adrenergic receptor stimulation in dogs susceptible to lethal arrhythmias. J Appl Physiol 91:1627-37
Altschuld, R A; Billman, G E (2000) beta(2)-Adrenoceptors and ventricular fibrillation. Pharmacol Ther 88:14-Jan
Carnes, C A; Mehdirad, A A (2000) Effects of azimilide, acidemia, and the combination on defibrillation energy requirements. J Cardiovasc Pharmacol 36:283-7
Mehdirad, A A; Carnes, C A; Nelson, S D (1999) The influence of specific and nonspecific potassium current blockade on the defibrillation energy requirement of biphasic shock. Pacing Clin Electrophysiol 22:147-51
Hohl, C M (1999) AMP deaminase in piglet cardiac myocytes: effect on nucleotide metabolism during ischemia. Am J Physiol 276:H1502-10
Carnes, C A; Mehdirad, A A; Nelson, S D (1998) Drug and defibrillator interactions. Pharmacotherapy 18:516-25
Matlib, M A; Zhou, Z; Knight, S et al. (1998) Oxygen-bridged dinuclear ruthenium amine complex specifically inhibits Ca2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes. J Biol Chem 273:10223-31
Starling, R C; Hammer, D F; Altschuld, R A (1998) Human myocardial ATP content and in vivo contractile function. Mol Cell Biochem 180:171-7
Billman, G E; Castillo, L C; Hensley, J et al. (1997) Beta2-adrenergic receptor antagonists protect against ventricular fibrillation: in vivo and in vitro evidence for enhanced sensitivity to beta2-adrenergic stimulation in animals susceptible to sudden death. Circulation 96:1914-22
Hensley, J; Billman, G E; Johnson, J D et al. (1997) Effects of calcium channel antagonists on Ca2+ transients in rat and canine cardiomyocytes. J Mol Cell Cardiol 29:1037-43

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