Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL036982-12
Application #
6080687
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1987-07-01
Project End
2000-02-29
Budget Start
1998-03-01
Budget End
1999-02-28
Support Year
12
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
North Carolina State University Raleigh
Department
Anatomy/Cell Biology
Type
Schools of Veterinary Medicine
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695

  Publications

Chen, Ching-Hsien; Cheng, Chun-Ting; Yuan, Yuan et al. (2015) Elevated MARCKS phosphorylation contributes to unresponsiveness of breast cancer to paclitaxel treatment. Oncotarget 6:15194-208
Chen, C-H; Thai, P; Yoneda, K et al. (2014) A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene 33:3696-706
Chen, Ching-Hsien; Chiu, Chun-Lung; Adler, Kenneth B et al. (2014) A novel predictor of cancer malignancy: up-regulation of myristoylated alanine-rich C kinase substrate phosphorylation in lung cancer. Am J Respir Crit Care Med 189:1002-4
Chen, Ching-Hsien; Statt, Sarah; Chiu, Chun-Lung et al. (2014) Targeting myristoylated alanine-rich C kinase substrate phosphorylation site domain in lung cancer. Mechanisms and therapeutic implications. Am J Respir Crit Care Med 190:1127-38
Foster, W Michael; Adler, Kenneth B; Crews, Anne L et al. (2010) MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac. Am J Physiol Lung Cell Mol Physiol 299:L345-52
Park, Jin-Ah; Crews, Anne L; Lampe, William R et al. (2007) Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein. Am J Pathol 171:1822-30
Chorley, Brian N; Crews, Anne L; Li, Yuehua et al. (2006) Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. Respir Res 7:35
Singer, Monique; Martin, Linda D; Vargaftig, B Boris et al. (2004) A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. Nat Med 10:193-6
Krunkosky, Thomas M; Martin, Linda D; Fischer, Bernard M et al. (2003) Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. Free Radic Biol Med 35:1158-67
Martin, Linda D; Adler, Kenneth B; Akley, Nancy J et al. (2002) Secretion-competent mouse tracheal epithelial cell culture from the genetically altered mouse: pathway analysis via gene array. Chest 121:79S

Showing the most recent 10 out of 40 publications