Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL037001-11
Application #
2218340
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1988-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pathology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Hatada, Seigo; Walton, William; Hatada, Tomoko et al. (2011) Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells. Exp Hematol 39:375-83, 383.e1-4
Koller, Beverly H; Marrack, Philippa; Kappler, John W et al. (2010) Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. J Immunol 184:4592-5
Ciavatta, Dominic; Kalantry, Sundeep; Magnuson, Terry et al. (2006) A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation. Proc Natl Acad Sci U S A 103:9958-63
Fair, Jeffrey H; Cairns, Bruce A; Lapaglia, Michael A et al. (2005) Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro. Proc Natl Acad Sci U S A 102:2958-63
Hatada, Seigo; Arnold, Larry W; Hatada, Tomoko et al. (2005) Isolating gene-corrected stem cells without drug selection. Proc Natl Acad Sci U S A 102:16357-61
Cohen, Stephanie M; Hatada, Seigo; Brylawski, Bruna P et al. (2004) Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences. Genomics 84:475-84
Ellmers, Leigh J; Knowles, J W; Kim, H-S et al. (2002) Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis. Am J Physiol Heart Circ Physiol 283:H707-14
Hatada, S; Nikkuni, K; Bentley, S A et al. (2000) Gene correction in hematopoietic progenitor cells by homologous recombination. Proc Natl Acad Sci U S A 97:13807-11
Kirby, S; Walton, W; Smithies, O (2000) Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation. Blood 95:3710-5
Cook, D N; Smithies, O; Strieter, R M et al. (1999) CD8+ T cells are a biologically relevant source of macrophage inflammatory protein-1 alpha in vivo. J Immunol 162:5423-8

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