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Kim, Chai-Wan; Moon, Young-Ah; Park, Sahng Wook et al. (2010) Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis. Proc Natl Acad Sci U S A 107:9626-31
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McNutt, Markey C; Kwon, Hyock Joo; Chen, Chiyuan et al. (2009) Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem 284:10561-70
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Moon, Young-Ah; Hammer, Robert E; Horton, Jay D (2009) Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice. J Lipid Res 50:412-23
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Kwon, Hyock Joo; Lagace, Thomas A; McNutt, Markey C et al. (2008) Molecular basis for LDL receptor recognition by PCSK9. Proc Natl Acad Sci U S A 105:1820-5
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Grefhorst, Aldo; McNutt, Markey C; Lagace, Thomas A et al. (2008) Plasma PCSK9 preferentially reduces liver LDL receptors in mice. J Lipid Res 49:1303-11
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Lagace, Thomas A; Curtis, David E; Garuti, Rita et al. (2006) Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice. J Clin Invest 116:2995-3005
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Rashid, Shirya; Curtis, David E; Garuti, Rita et al. (2005) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. Proc Natl Acad Sci U S A 102:5374-9
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Park, Sahng Wook; Moon, Young-Ah; Horton, Jay D (2004) Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. J Biol Chem 279:50630-8
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Browning, Jeffrey D; Horton, Jay D (2004) Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114:147-52
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Moon, Young-Ah; Horton, Jay D (2003) Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade. J Biol Chem 278:7335-43
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Showing the most recent 10 out of 29 publications
