Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL039757-13
Application #
6605665
Study Section
Cardiovascular and Renal Study Section (CVB)
Program Officer
Rabadan-Diehl, Cristina
Project Start
1988-08-01
Project End
2005-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
13
Fiscal Year
2003
Total Cost
$267,750
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Wu, Nan; Hanson, Susan M; Francis, Derek J et al. (2006) Arrestin binding to calmodulin: a direct interaction between two ubiquitous signaling proteins. J Mol Biol 364:955-63
Wu, Nan; Macion-Dazard, Rosemarie; Nithianantham, Stanley et al. (2006) Soluble mimics of the cytoplasmic face of the human V1-vascular vasopressin receptor bind arrestin2 and calmodulin. Mol Pharmacol 70:249-58
Macion-Dazard, Rosemarie; Callahan, Nicholas; Xu, Zhen et al. (2006) Mapping the binding site of six nonpeptide antagonists to the human V2-renal vasopressin receptor. J Pharmacol Exp Ther 316:564-71
Adikesavan, Nallini Vijayarangan; Mahmood, Syed Saad; Stanley, Nithianantham et al. (2005) A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein. Acta Crystallogr Sect F Struct Biol Cryst Commun 61:341-5
Thibonnier, Marc (2003) Vasopressin receptor antagonists in heart failure. Curr Opin Pharmacol 3:683-7
Thibonnier, M; Plesnicher, C L; Berrada, K et al. (2001) Role of the human V1 vasopressin receptor COOH terminus in internalization and mitogenic signal transduction. Am J Physiol Endocrinol Metab 281:E81-92
Thibonnier, M; Graves, M K; Wagner, M S et al. (2000) Study of V(1)-vascular vasopressin receptor gene microsatellite polymorphisms in human essential hypertension. J Mol Cell Cardiol 32:557-64
Berrada, K; Plesnicher, C L; Luo, X et al. (2000) Dynamic interaction of human vasopressin/oxytocin receptor subtypes with G protein-coupled receptor kinases and protein kinase C after agonist stimulation. J Biol Chem 275:27229-37
Thibonnier, M; Coles, P; Conarty, D M et al. (2000) A molecular model of agonist and nonpeptide antagonist binding to the human V(1) vascular vasopressin receptor. J Pharmacol Exp Ther 294:195-203
Thibonnier, M; Conarty, D M; Plesnicher, C L (2000) Mediators of the mitogenic action of human V(1) vascular vasopressin receptors. Am J Physiol Heart Circ Physiol 279:H2529-39

Showing the most recent 10 out of 23 publications