Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL041307-04S1
Application #
3359007
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1989-04-01
Project End
1994-03-31
Budget Start
1992-09-23
Budget End
1993-03-31
Support Year
4
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Hilal-Dandan, Randa; He, Huaping; Martin, Jody L et al. (2009) Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: regulation by pertussis toxin-sensitive Gi protein and cAMP. Am J Physiol Heart Circ Physiol 296:H728-34
Akamine, Pearl; Madhusudan; Brunton, Laurence L et al. (2004) Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit. Biochemistry 43:85-96
Ostrom, Rennolds S; Naugle, Jennifer E; Hase, Miki et al. (2003) Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts. J Biol Chem 278:24461-8
Zambon, A C; Brunton, L L; Barrett, K E et al. (2001) Cloning, expression, signaling mechanisms, and membrane targeting of P2Y(11) receptors in Madin Darby canine kidney cells. Mol Pharmacol 60:26-35
Zambon, A C; Hughes, R J; Meszaros, J G et al. (2000) P2Y(2) receptor of MDCK cells: cloning, expression, and cell-specific signaling. Am J Physiol Renal Physiol 279:F1045-52
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Hilal-Dandan, R; Kanter, J R; Brunton, L L (2000) Characterization of G-protein signaling in ventricular myocytes from the adult mouse heart: differences from the rat. J Mol Cell Cardiol 32:1211-21
Meszaros, J G; Gonzalez, A M; Endo-Mochizuki, Y et al. (2000) Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G(q) and G(s). Am J Physiol Cell Physiol 278:C154-62
Gustafsson, A B; Brunton, L L (2000) beta-adrenergic stimulation of rat cardiac fibroblasts enhances induction of nitric-oxide synthase by interleukin-1beta via message stabilization. Mol Pharmacol 58:1470-8
Setyawan, J; Koide, K; Diller, T C et al. (1999) Inhibition of protein kinases by balanol: specificity within the serine/threonine protein kinase subfamily. Mol Pharmacol 56:370-6

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