Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL041315-03
Application #
3359033
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1988-07-01
Project End
1992-06-30
Budget Start
1990-07-01
Budget End
1991-06-30
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Chen, Jin; Hoffman, Brian B; Isseroff, R Rivkah (2002) Beta-adrenergic receptor activation inhibits keratinocyte migration via a cyclic adenosine monophosphate-independent mechanism. J Invest Dermatol 119:1261-8
Hu, Zhuo-Wei; Kerb, Reinhold; Shi, Xiao-You et al. (2002) Angiotensin II increases expression of cyclooxygenase-2: implications for the function of vascular smooth muscle cells. J Pharmacol Exp Ther 303:563-73
Hu, Z W; Hoffman, B B (2000) Nuclear run-on assays for measurement of adrenergic receptor transcription rate. Methods Mol Biol 126:169-80
Hu, Z W; Shi, X Y; Lin, R Z et al. (1999) alpha1-Adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase. J Pharmacol Exp Ther 290:28-37
Hu, Z W; Shi, X Y; Lin, R Z et al. (1999) Contrasting signaling pathways of alpha1A- and alpha1B-adrenergic receptor subtype activation of phosphatidylinositol 3-kinase and Ras in transfected NIH3T3 cells. Mol Endocrinol 13:3-14
Chen, J; Lin, R; Hu, Z W et al. (1999) alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+. J Pharmacol Exp Ther 289:1376-84
Hu, Z W; Shi, X Y; Hoffman, B B (1998) Doxazosin inhibits proliferation and migration of human vascular smooth-muscle cells independent of alpha1-adrenergic receptor antagonism. J Cardiovasc Pharmacol 31:833-9
Lin, R Z; Chen, J; Hu, Z W et al. (1998) Phosphorylation of the cAMP response element-binding protein and activation of transcription by alpha1 adrenergic receptors. J Biol Chem 273:30033-8
Lin, R Z; Hu, Z W; Chin, J H et al. (1997) Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts. J Biol Chem 272:31196-202
Okazaki, M; Hu, Z W; Fujinaga, M et al. (1996) Alpha 1 adrenergic receptor activation of proto-oncogene expression in arterial smooth muscle: regulation by nitric oxide and vascular injury. Recept Signal Transduct 6:165-78

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