Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL041587-15
Application #
6741453
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Noel, Patricia
Project Start
1988-12-01
Project End
2006-04-30
Budget Start
2004-05-01
Budget End
2006-04-30
Support Year
15
Fiscal Year
2004
Total Cost
$316,000
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Dib, Marwan; Zsengeller, Zsuzsanna; Mitsialis, Alex et al. (2009) A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol 297:L687-97
Saban, Ricardo; Gerard, Norma P; Saban, Marcia R et al. (2002) Mast cells mediate substance P-induced bladder inflammation through an NK(1) receptor-independent mechanism. Am J Physiol Renal Physiol 283:F616-29
Vergnolle, N; Bunnett, N W; Sharkey, K A et al. (2001) Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway. Nat Med 7:821-6
Saban, R; Saban, M R; Nguyen, N B et al. (2000) Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis. Am J Pathol 156:775-80
Grasemann, H; Lu, B; Jiao, A et al. (1999) Targeted deletion of the neutral endopeptidase gene alters ventilatory responses to acute hypoxia in mice. J Appl Physiol 87:1266-71
Bhatia, M; Saluja, A K; Hofbauer, B et al. (1998) Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury. Proc Natl Acad Sci U S A 95:4760-5
Garcia Rodriguez, C; Cundell, D R; Tuomanen, E I et al. (1995) The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking. J Biol Chem 270:25178-84
Gerard, C; Gerard, N P (1994) C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu Rev Immunol 12:775-808
Iijima, H; Gerard, N P; Squassoni, C et al. (1992) Exon 16 del: a novel form of human neutral endopeptidase (CALLA). Am J Physiol 262:L725-9
Bao, L; Gerard, N P; Eddy Jr, R L et al. (1992) Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. Genomics 13:437-40

Showing the most recent 10 out of 13 publications